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Identification of a soluble guanylate cyclase in RBCs: preserved activity in patients with coronary artery disease

Endothelial dysfunction is associated with decreased NO bioavailability and impaired activation of the NO receptor soluble guanylate cyclase (sGC) in the vasculature and in platelets. Red blood cells (RBCs) are known to produce NO under hypoxic and normoxic conditions; however evidence of expression...

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Detalles Bibliográficos
Autores principales: Cortese-Krott, Miriam M., Mergia, Evanthia, Kramer, Christian M., Lückstädt, Wiebke, Yang, Jiangning, Wolff, Georg, Panknin, Christina, Bracht, Thilo, Sitek, Barbara, Pernow, John, Stasch, Johannes-Peter, Feelisch, Martin, Koesling, Doris, Kelm, Malte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975213/
https://www.ncbi.nlm.nih.gov/pubmed/29024896
http://dx.doi.org/10.1016/j.redox.2017.08.020