Integrin CD11b mediates α-synuclein-induced activation of NADPH oxidase through a Rho-dependent pathway

The activation of microglial NADPH oxidase (NOX2) induced by α-synuclein has been implicated in Parkinson's disease (PD) and other synucleinopathies. However, how α-synuclein activates NOX2 remains unclear. Previous study revealed that both toll-like receptor 2 (TLR2) and integrin play importan...

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Detalles Bibliográficos
Autores principales: Hou, Liyan, Bao, Xiuqi, Zang, Caixia, Yang, Hanyu, Sun, Fuqiang, Che, Yuning, Wu, Xuefei, Li, Shao, Zhang, Dan, Wang, Qingshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975218/
https://www.ncbi.nlm.nih.gov/pubmed/29154191
http://dx.doi.org/10.1016/j.redox.2017.11.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975218/
https://www.ncbi.nlm.nih.gov/pubmed/29154191
http://dx.doi.org/10.1016/j.redox.2017.11.010

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