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Advanced oxidation protein products induce S-phase arrest of hepatocytes via the ROS-dependent, β-catenin-CDK2-mediated pathway

Liver regeneration has important clinical importance in the setting of partial hepatectomy (PH). Following PH, quiescent hepatocytes can reenter cell cycle to restore liver mass. Hepatocyte cell cycle progression, as the basic motivations of liver regeneration, can be disrupted by multiple pathologi...

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Detalles Bibliográficos
Autores principales: Sun, Shibo, Xie, Fang, Xu, Xiaoping, Cai, Qing, Zhang, Qifan, Cui, Zhonglin, Zheng, Yujian, Zhou, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975226/
https://www.ncbi.nlm.nih.gov/pubmed/29032312
http://dx.doi.org/10.1016/j.redox.2017.09.011