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Advanced oxidation protein products induce S-phase arrest of hepatocytes via the ROS-dependent, β-catenin-CDK2-mediated pathway
Liver regeneration has important clinical importance in the setting of partial hepatectomy (PH). Following PH, quiescent hepatocytes can reenter cell cycle to restore liver mass. Hepatocyte cell cycle progression, as the basic motivations of liver regeneration, can be disrupted by multiple pathologi...
Autores principales: | Sun, Shibo, Xie, Fang, Xu, Xiaoping, Cai, Qing, Zhang, Qifan, Cui, Zhonglin, Zheng, Yujian, Zhou, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975226/ https://www.ncbi.nlm.nih.gov/pubmed/29032312 http://dx.doi.org/10.1016/j.redox.2017.09.011 |
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