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Oxalate induces mitochondrial dysfunction and disrupts redox homeostasis in a human monocyte derived cell line

Monocytes/macrophages are thought to be recruited to the renal interstitium during calcium oxalate (CaOx) kidney stone disease for crystal clearance. Mitochondria play an important role in monocyte function during the immune response. We recently determined that monocytes in patients with CaOx kidne...

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Detalles Bibliográficos
Autores principales: Patel, Mikita, Yarlagadda, Vidhush, Adedoyin, Oreoluwa, Saini, Vikram, Assimos, Dean G., Holmes, Ross P., Mitchell, Tanecia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975227/
https://www.ncbi.nlm.nih.gov/pubmed/29272854
http://dx.doi.org/10.1016/j.redox.2017.12.003