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Oxalate induces mitochondrial dysfunction and disrupts redox homeostasis in a human monocyte derived cell line
Monocytes/macrophages are thought to be recruited to the renal interstitium during calcium oxalate (CaOx) kidney stone disease for crystal clearance. Mitochondria play an important role in monocyte function during the immune response. We recently determined that monocytes in patients with CaOx kidne...
Autores principales: | Patel, Mikita, Yarlagadda, Vidhush, Adedoyin, Oreoluwa, Saini, Vikram, Assimos, Dean G., Holmes, Ross P., Mitchell, Tanecia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975227/ https://www.ncbi.nlm.nih.gov/pubmed/29272854 http://dx.doi.org/10.1016/j.redox.2017.12.003 |
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