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Egr-1 increases angiogenesis in cartilage via binding Netrin-1 receptor DCC promoter

BACKGROUND: Osteoarthritis (OA) is a joint disease characterized by degradation of cartilage. The etiology of OA is still unclear. Vascular endothelial growth factor (VEGF) plays a key role of angiogenesis in the pathogenesis of OA and contributes to the angiogenesis of NT-1/DCC. Whether or not NT-1...

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Detalles Bibliográficos
Autores principales: Sheng, Jun, Liu, Da, Kang, Xia, Chen, Ying, Jiang, Kai, Zheng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975438/
https://www.ncbi.nlm.nih.gov/pubmed/29843768
http://dx.doi.org/10.1186/s13018-018-0826-x