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Tyrphostin AG17 inhibits adipocyte differentiation in vivo and in vitro

BACKGROUND: Excessive subcutaneous adiposity in obesity is associated to positive white adipocyte tissue (WAT) differentiation (adipogenesis) and WAT expandability. Here, we hypothesized that supplementation with the insulin inhibitor and mitochondrial uncoupler, Tyrphostin (T-AG17), in vitro and in...

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Detalles Bibliográficos
Autores principales: Camacho, Alberto, Segoviano-Ramírez, Juan Carlos, Sánchez-Garcia, Adriana, de Jesus Herrera-de la Rosa, Jose, García-Juarez, Jaime, Hernandez-Puente, Carlos Alberto, Calvo-Anguiano, Geovana, Maltos-Uro, Sergio Rodolfo, Olguin, Alejandra, Gojon-Romanillos, Gabriel, Gojon-Zorrilla, Gabriel, Ortiz-Lopez, Rocio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975476/
https://www.ncbi.nlm.nih.gov/pubmed/29843731
http://dx.doi.org/10.1186/s12944-018-0784-7