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APOBEC3B up-regulation independently predicts ovarian cancer prognosis: a cohort study

BACKGROUND: Ovarian cancer is a heterogeneous disease with a high degree of genomic instability, pro-/antitumor immunity and inflammation, and remains the most lethal gynecologic cancer worldwide. APOBEC3B, a member of the AID/APOBEC family, is part of the innate immune system which plays a key role...

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Detalles Bibliográficos
Autores principales: Du, Yan, Tao, Xiang, Wu, Jing, Yu, Huandi, Yu, Yinhua, Zhao, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975489/
https://www.ncbi.nlm.nih.gov/pubmed/29853799
http://dx.doi.org/10.1186/s12935-018-0572-5