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ARL2 overexpression inhibits glioma proliferation and tumorigenicity via down-regulating AXL

BACKGROUND: Glioma is the most common primary brain tumor in adults with a poor prognosis. As a member of ARF subfamily GTPase, ARL2 plays a key role in regulating the dynamics of microtubules and mitochondrial functions. Recently, ARL2 has been identified as a prognostic and therapeutic target in a...

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Detalles Bibliográficos
Autores principales: Wang, Yulin, Guan, Gefei, Cheng, Wen, Jiang, Yang, Shan, Fengping, Wu, Anhua, Cheng, Peng, Guo, Zongze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975491/
https://www.ncbi.nlm.nih.gov/pubmed/29843637
http://dx.doi.org/10.1186/s12885-018-4517-0