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ARL2 overexpression inhibits glioma proliferation and tumorigenicity via down-regulating AXL
BACKGROUND: Glioma is the most common primary brain tumor in adults with a poor prognosis. As a member of ARF subfamily GTPase, ARL2 plays a key role in regulating the dynamics of microtubules and mitochondrial functions. Recently, ARL2 has been identified as a prognostic and therapeutic target in a...
Autores principales: | Wang, Yulin, Guan, Gefei, Cheng, Wen, Jiang, Yang, Shan, Fengping, Wu, Anhua, Cheng, Peng, Guo, Zongze |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975491/ https://www.ncbi.nlm.nih.gov/pubmed/29843637 http://dx.doi.org/10.1186/s12885-018-4517-0 |
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