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Age-related DNA methylation changes are tissue-specific with ELOVL2 promoter methylation as exception

BACKGROUND: The well-established association of chronological age with changes in DNA methylation is primarily founded on the analysis of large sets of blood samples, while conclusions regarding tissue-specificity are typically based on small number of samples, tissues and CpGs. Here, we systematica...

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Detalles Bibliográficos
Autores principales: Slieker, Roderick C., Relton, Caroline L., Gaunt, Tom R., Slagboom, P. Eline, Heijmans, Bastiaan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975493/
https://www.ncbi.nlm.nih.gov/pubmed/29848354
http://dx.doi.org/10.1186/s13072-018-0191-3