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Age-related DNA methylation changes are tissue-specific with ELOVL2 promoter methylation as exception
BACKGROUND: The well-established association of chronological age with changes in DNA methylation is primarily founded on the analysis of large sets of blood samples, while conclusions regarding tissue-specificity are typically based on small number of samples, tissues and CpGs. Here, we systematica...
Autores principales: | Slieker, Roderick C., Relton, Caroline L., Gaunt, Tom R., Slagboom, P. Eline, Heijmans, Bastiaan T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975493/ https://www.ncbi.nlm.nih.gov/pubmed/29848354 http://dx.doi.org/10.1186/s13072-018-0191-3 |
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