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Soluble epoxide hydrolase inhibitors, t-AUCB, downregulated miR-133 in a mouse model of myocardial infarction

BACKGROUND: It has been demonstrated that soluble epoxide hydrolase inhibitors (sEHIs) are protective against ischemia-induced lethal arrhythmias, but the mechanisms involved are unknown. Previously, we showed that sEHIs might reduce the incidence of ischemic arrhythmias by suppressing microRNA-1 (m...

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Detalles Bibliográficos
Autores principales: Gui, Yajun, Li, Da, Chen, Jingyuan, Wang, Yating, Hu, Jiahui, Liao, Caixiu, Deng, Limin, Xiang, Qunyan, Yang, Tao, Du, Xiao, Zhang, Shilan, Xu, Danyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975509/
https://www.ncbi.nlm.nih.gov/pubmed/29843720
http://dx.doi.org/10.1186/s12944-018-0780-y