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Grifolic acid induces GH3 adenoma cell death by inhibiting ATP production through a GPR120-independent mechanism

BACKGROUND: Grifolic acid is a derivative of grifolin, an antitumor natural compound, and it was reported as an agonist of free fatty acid receptor GPR120. Little is known about its antitumor effects and the involvement of GPR120. METHODS: GH3 cells, the rat anterior pituitary adenoma cells, were cu...

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Detalles Bibliográficos
Autores principales: Zhao, Yufeng, Zhang, Lei, Yan, Aili, Chen, Di, Xie, Rong, Liu, Yingguang, Liang, Xiangyan, Zhao, Yanyan, Wei, Lanlan, Yu, Jun, Xu, Xi, Su, Xingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975534/
https://www.ncbi.nlm.nih.gov/pubmed/29843779
http://dx.doi.org/10.1186/s40360-018-0215-4