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Grifolic acid induces GH3 adenoma cell death by inhibiting ATP production through a GPR120-independent mechanism
BACKGROUND: Grifolic acid is a derivative of grifolin, an antitumor natural compound, and it was reported as an agonist of free fatty acid receptor GPR120. Little is known about its antitumor effects and the involvement of GPR120. METHODS: GH3 cells, the rat anterior pituitary adenoma cells, were cu...
Autores principales: | Zhao, Yufeng, Zhang, Lei, Yan, Aili, Chen, Di, Xie, Rong, Liu, Yingguang, Liang, Xiangyan, Zhao, Yanyan, Wei, Lanlan, Yu, Jun, Xu, Xi, Su, Xingli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975534/ https://www.ncbi.nlm.nih.gov/pubmed/29843779 http://dx.doi.org/10.1186/s40360-018-0215-4 |
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