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miR-134 increases the antitumor effects of cytarabine by targeting Mnks in acute myeloid leukemia cells
The relapse and resistance to cytarabine (Ara-C) therapy is still a dominating obstacle to the successful clinical treatment of acute myeloid leukemia (AML). Recent studies have shown that dysregulation of miRNAs might modulate the resistance of cancer cells to anticancer drugs; yet, the mechanism i...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975600/ https://www.ncbi.nlm.nih.gov/pubmed/29872325 http://dx.doi.org/10.2147/OTT.S143465 |