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miR-134 increases the antitumor effects of cytarabine by targeting Mnks in acute myeloid leukemia cells

The relapse and resistance to cytarabine (Ara-C) therapy is still a dominating obstacle to the successful clinical treatment of acute myeloid leukemia (AML). Recent studies have shown that dysregulation of miRNAs might modulate the resistance of cancer cells to anticancer drugs; yet, the mechanism i...

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Detalles Bibliográficos
Autores principales:	Chen, Kankan, Chen, Yue, Chen, Zhi, Shi, Yuye, He, Zhengmei, Ding, Banghe, Wang, Chunling, Yu, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975600/ https://www.ncbi.nlm.nih.gov/pubmed/29872325 http://dx.doi.org/10.2147/OTT.S143465

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