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Inhibition of survivin enhances radiosensitivity of esophageal cancer cells by switching radiation-induced senescence to apoptosis

PURPOSE: Strategies to increase radiosensitivity are urgently needed. Combining radiosensitizing reagents with radiotherapy could improve the outcome of cancer treatment. Some preclinical studies showed that sepantronium bromide (YM155) could sensitize cancer cells to radiation by inhibiting the sur...

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Detalles Bibliográficos
Autores principales: Liu, Xianghe, Zhao, Yahui, Zhang, Weina, Gao, Yang, Huo, Miaomiao, Liu, Mei, Xiao, Zefen, Liang, Shufang, Xu, Ningzhi, Zhu, Hongxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975611/
https://www.ncbi.nlm.nih.gov/pubmed/29872320
http://dx.doi.org/10.2147/OTT.S166798