Cargando…

Inhibition of survivin enhances radiosensitivity of esophageal cancer cells by switching radiation-induced senescence to apoptosis

PURPOSE: Strategies to increase radiosensitivity are urgently needed. Combining radiosensitizing reagents with radiotherapy could improve the outcome of cancer treatment. Some preclinical studies showed that sepantronium bromide (YM155) could sensitize cancer cells to radiation by inhibiting the sur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Xianghe, Zhao, Yahui, Zhang, Weina, Gao, Yang, Huo, Miaomiao, Liu, Mei, Xiao, Zefen, Liang, Shufang, Xu, Ningzhi, Zhu, Hongxia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975611/ https://www.ncbi.nlm.nih.gov/pubmed/29872320 http://dx.doi.org/10.2147/OTT.S166798

Ejemplares similares

Overexpression of KLF4 promotes cell senescence through microRNA-203-survivin-p21 pathway
por: Xu, Qing, et al.
Publicado: (2016)

Polarization of macrophages in the tumor microenvironment is influenced by EGFR signaling within colon cancer cells
por: Zhang, Weina, et al.
Publicado: (2016)

EGFR-IL-6 Signaling Axis Mediated the Inhibitory Effect of Methylseleninic Acid on Esophageal Squamous Cell Carcinoma
por: Wang, Yu, et al.
Publicado: (2021)

XBP1 regulates the protumoral function of tumor-associated macrophages in human colorectal cancer
por: Zhao, Yahui, et al.
Publicado: (2021)

EGFR targeting enhances the efficiency of chemotherapy through inhibiting IRE1α-XBP1s pathway in colorectal cancer cells
por: Huo, Miaomiao, et al.
Publicado: (2020)

MiR-338-5p enhances the radiosensitivity of esophageal squamous cell carcinoma by inducing apoptosis through targeting survivin
por: Park, Misun, et al.
Publicado: (2017)

TAZ promotes cell growth and inhibits Celastrol-induced cell apoptosis
por: Wang, Shuren, et al.
Publicado: (2016)

Growth inhibition and chemo-radiosensitization of esophageal squamous cell carcinoma by survivin-shRNA lentivirus transfection
por: Zhou, Changlin, et al.
Publicado: (2018)

Overexpression of the DEC1 Protein Induces Senescence In Vitro and Is Related to Better Survival in Esophageal Squamous Cell Carcinoma
por: Xu, Qing, et al.
Publicado: (2012)

Expression of epidermal growth factor receptor is an independent prognostic factor for esophageal squamous cell carcinoma
por: Wang, Qifeng, et al.
Publicado: (2013)

FoxM1 knockdown enhanced radiosensitivity of esophageal cancer by inducing apoptosis
por: Qin, Qin, et al.
Publicado: (2023)

Survivin withdrawal by nuclear export failure as a physiological switch to commit cells to apoptosis
por: Chan, K-S, et al.
Publicado: (2010)

IL-6 influences the polarization of macrophages and the formation and growth of colorectal tumor
por: Chen, Lechuang, et al.
Publicado: (2018)

Small-molecule survivin inhibitor YM155 enhances radiosensitization in esophageal squamous cell carcinoma by the abrogation of G(2) checkpoint and suppression of homologous recombination repair
por: Qin, Qin, et al.
Publicado: (2014)

The role of human antigen R (HuR) in modulating proliferation, senescence and radiosensitivity of skin cells
por: Yu, Daojiang, et al.
Publicado: (2022)

Repurposing cephalosporin antibiotics as pro-senescent radiosensitizers
por: Labay, Edwardine, et al.
Publicado: (2016)

Survivin splice variants are not essential for mitotic progression or inhibition of apoptosis induced by doxorubicin and radiation
por: Jacob, Naduparambil K, et al.
Publicado: (2012)

Increased radiosensitivity and radiation-induced apoptosis in SRC-3 knockout mice
por: Jin, Jie, et al.
Publicado: (2014)

Centrosome amplification induced by survivin suppression enhances both chromosome instability and radiosensitivity in glioma cells
por: Saito, T, et al.
Publicado: (2008)

Analysis of Curcumin as a Radiosensitizer in Cancer Therapy with Serum Survivin Examination: Randomised Control Trial
por: Hidayat, Yudi Mulyana, et al.
Publicado: (2021)

Survivin induces defects in apoptosis in eosinophils in intestine with food allergy
por: Gao, Han, et al.
Publicado: (2019)

An otoprotective role for the apoptosis inhibitor protein survivin
por: Knauer, S K, et al.
Publicado: (2010)

Clinical correlation of nuclear survivin in esophageal squamous cell carcinoma
por: Hui, Marco K. C., et al.
Publicado: (2012)

A Preoperative Measurement of Serum MicroRNA-125b May Predict the Presence of Microvascular Invasion in Hepatocellular Carcinomas Patients
por: Liu, Mei, et al.
Publicado: (2016)

Significance of Nuclear Factor-Kappa B (NF-κB) and Survivin in Breast Cancer and Their Association with Radiosensitivity and Prognosis
por: Cao, Qian, et al.
Publicado: (2023)

Survivin Regulates Bad Gene Expression by Binding to Its Promoter and Modulates Cell Cycle and Apoptosis in Esophageal Carcinoma Cell
por: Chen, Yan, et al.
Publicado: (2021)

Analysis of the expression levels of survivin and VEGF in patients with acute lymphoblastic leukemia
por: YANG, MAN, et al.
Publicado: (2013)

MicroRNA-148b enhances the radiosensitivity of non-Hodgkin's Lymphoma cells by promoting radiation-induced apoptosis
por: Wu, Yong, et al.
Publicado: (2012)

Targeting senescence-like fibroblasts radiosensitizes non–small cell lung cancer and reduces radiation-induced pulmonary fibrosis
por: Meng, Jingshu, et al.
Publicado: (2021)

Expression of SIRT1 and survivin correlates with poor prognosis in esophageal squamous cell carcinoma
por: Yan, Li, et al.
Publicado: (2020)

Keap1 controls protein S-nitrosation and apoptosis-senescence switch in endothelial cells
por: Kopacz, Aleksandra, et al.
Publicado: (2019)

Survivin knockdown induces senescence in TTF-1-expressing, KRAS-mutant lung adenocarcinomas
por: Sumi, Toshiyuki, et al.
Publicado: (2018)

Apatinib enhances the radiosensitivity of the esophageal cancer cell line KYSE-150 by inducing apoptosis and cell cycle redistribution
por: Hu, Lijun, et al.
Publicado: (2019)

Survivin small interfering RNA suppresses glioblastoma growth by inducing cellular apoptosis☆
por: Liu, Yanbo, et al.
Publicado: (2012)

Foretinib Enhances the Radiosensitivity in Esophageal Squamous Cell Carcinoma by Inhibiting Phosphorylation of c-Met
por: Chen, Guang-Zong, et al.
Publicado: (2017)

Discovery of Novel 3-Cyanopyridines as Survivin Modulators and Apoptosis Inducers
por: Sabour, Rehab, et al.
Publicado: (2020)

Targeting survivin sensitizes cervical cancer cells to radiation treatment
por: Zhou, Jing, et al.
Publicado: (2020)

Prognostic Utility of Apoptosis Index, Ki-67 and Survivin Expression in Dogs with Nasal Carcinoma Treated with Orthovoltage Radiation Therapy
por: FU, Dah-Renn, et al.
Publicado: (2014)

Downregulation of survivin by adenovirus-mediated shRNA promotes apoptosis in skin cancer cells
por: Hao, Yuqin, et al.
Publicado: (2019)

Delineating the Switch between Senescence and Apoptosis in Cervical Cancer Cells under Ciclopirox Treatment
por: Herrmann, Anja L., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_l48i30grtussgon5u318eovcn7