BGP: identifying gene-specific branching dynamics from single-cell data with a branching Gaussian process

High-throughput single-cell gene expression experiments can be used to uncover branching dynamics in cell populations undergoing differentiation through pseudotime methods. We develop the branching Gaussian process (BGP), a non-parametric model that is able to identify branching dynamics for individ...

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Detalles Bibliográficos
Autores principales: Boukouvalas, Alexis, Hensman, James, Rattray, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975664/
https://www.ncbi.nlm.nih.gov/pubmed/29843817
http://dx.doi.org/10.1186/s13059-018-1440-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975664/
https://www.ncbi.nlm.nih.gov/pubmed/29843817
http://dx.doi.org/10.1186/s13059-018-1440-2

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