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BGP: identifying gene-specific branching dynamics from single-cell data with a branching Gaussian process
High-throughput single-cell gene expression experiments can be used to uncover branching dynamics in cell populations undergoing differentiation through pseudotime methods. We develop the branching Gaussian process (BGP), a non-parametric model that is able to identify branching dynamics for individ...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975664/ https://www.ncbi.nlm.nih.gov/pubmed/29843817 http://dx.doi.org/10.1186/s13059-018-1440-2 |