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Preparation of an epitope-based recombinant diagnostic antigen specific to anti-phospholipase A(2) receptor 1 antibodies

BACKGROUND: According to recent studies, the phospholipase A2 receptor 1 (PLA(2)R1) may be used as a biomarker to diagnose idiopathic membranous nephropathy (iMN). Moreover, the immune-dominant regions of PLA(2)R1 have been identified. The aim of the present study was to construct a diagnostic antig...

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Detalles Bibliográficos
Autores principales: Li, Hua, Xu, Yonghua, Yang, Weiming, Huang, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975665/
https://www.ncbi.nlm.nih.gov/pubmed/29843797
http://dx.doi.org/10.1186/s12896-018-0448-8