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Activity modulation and allosteric control of a scaffolded DNAzyme using a dynamic DNA nanostructure

Recognition of the fundamental importance of allosteric regulation in biology dates back to not long after its discovery in the 1960s. Our ability to rationally engineer this potentially useful property into normally non-allosteric catalysts, however, remains limited. In response we report a DNA nan...

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Detalles Bibliográficos
Autores principales: Mao, Xiuhai, Simon, Anna J., Pei, Hao, Shi, Jiye, Li, Jiang, Huang, Qing, Plaxco, Kevin W., Fan, Chunhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975834/
https://www.ncbi.nlm.nih.gov/pubmed/29910875
http://dx.doi.org/10.1039/c5sc03705k