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Activity modulation and allosteric control of a scaffolded DNAzyme using a dynamic DNA nanostructure
Recognition of the fundamental importance of allosteric regulation in biology dates back to not long after its discovery in the 1960s. Our ability to rationally engineer this potentially useful property into normally non-allosteric catalysts, however, remains limited. In response we report a DNA nan...
Autores principales: | Mao, Xiuhai, Simon, Anna J., Pei, Hao, Shi, Jiye, Li, Jiang, Huang, Qing, Plaxco, Kevin W., Fan, Chunhai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975834/ https://www.ncbi.nlm.nih.gov/pubmed/29910875 http://dx.doi.org/10.1039/c5sc03705k |
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