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Systematic study of the dynamics and half-lives of newly synthesized proteins in human cells

Protein dynamics are essential in regulating nearly every cellular event, and aberrant proteostasis is the source of many diseases. It is extraordinarily difficult to globally study protein dynamics and accurately measure their half-lives. Here we have developed a chemical proteomics method integrat...

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Detalles Bibliográficos
Autores principales: Chen, Weixuan, Smeekens, Johanna M., Wu, Ronghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975921/
https://www.ncbi.nlm.nih.gov/pubmed/29910897
http://dx.doi.org/10.1039/c5sc03826j