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Systematic study of the dynamics and half-lives of newly synthesized proteins in human cells
Protein dynamics are essential in regulating nearly every cellular event, and aberrant proteostasis is the source of many diseases. It is extraordinarily difficult to globally study protein dynamics and accurately measure their half-lives. Here we have developed a chemical proteomics method integrat...
Autores principales: | Chen, Weixuan, Smeekens, Johanna M., Wu, Ronghu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975921/ https://www.ncbi.nlm.nih.gov/pubmed/29910897 http://dx.doi.org/10.1039/c5sc03826j |
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