Linking coupled motions and entropic effects to the catalytic activity of 2-deoxyribose-5-phosphate aldolase (DERA)

DERA, 2-deoxyribose-5-phosphate aldolase, catalyzes the retro-aldol cleavage of 2-deoxy-ribose-5-phosphate (dR5P) into glyceraldehyde-3-phosphate (G3P) and acetaldehyde in a branch of the pentose phosphate pathway. In addition to the physiological reaction, DERA also catalyzes the reverse addition r...

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Detalles Bibliográficos
Autores principales: Ma, Huan, Szeler, Klaudia, Kamerlin, Shina C. L., Widersten, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975929/
https://www.ncbi.nlm.nih.gov/pubmed/29910900
http://dx.doi.org/10.1039/c5sc03666f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975929/
https://www.ncbi.nlm.nih.gov/pubmed/29910900
http://dx.doi.org/10.1039/c5sc03666f

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