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The role of beta cell heterogeneity in islet function and insulin release

It is becoming increasingly apparent that not all insulin-secreting beta cells are equal. Subtle differences exist at the transcriptomic and protein expression levels, with repercussions for beta cell survival/proliferation, calcium signalling and insulin release. Notably, beta cell heterogeneity di...

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Detalles Bibliográficos
Autores principales: Nasteska, Daniela, Hodson, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976077/
https://www.ncbi.nlm.nih.gov/pubmed/29661799
http://dx.doi.org/10.1530/JME-18-0011