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Molecular mechanisms of glucocorticoids on skeleton and bone regeneration after fracture

Glucocorticoid hormones (GCs) have profound effects on bone metabolism. Via their nuclear hormone receptor – the GR – they act locally within bone cells and modulate their proliferation, differentiation, and cell death. Consequently, high glucocorticoid levels – as present during steroid therapy or...

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Detalles Bibliográficos
Autores principales: Hachemi, Yasmine, Rapp, Anna E, Picke, Ann-Kristin, Weidinger, Gilbert, Ignatius, Anita, Tuckermann, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976078/
https://www.ncbi.nlm.nih.gov/pubmed/29588427
http://dx.doi.org/10.1530/JME-18-0024