Kynurenine pathway is altered in patients with SLE and associated with severe fatigue

OBJECTIVE: Fatigue has been reported as the most disturbing symptom in a majority of patients with SLE. Depression is common and often severe. Together these symptoms cause significant morbidity and affect patients with otherwise relatively mild disease. Tryptophan and its metabolites in the kynuren...

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Detalles Bibliográficos
Autores principales: Åkesson, Karolina, Pettersson, Susanne, Ståhl, Sara, Surowiec, Izabella, Hedenström, Mattias, Eketjäll, Susanna, Trygg, Johan, Jakobsson, Per-Johan, Gunnarsson, Iva, Svenungsson, Elisabet, Idborg, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976103/
https://www.ncbi.nlm.nih.gov/pubmed/29868176
http://dx.doi.org/10.1136/lupus-2017-000254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976103/
https://www.ncbi.nlm.nih.gov/pubmed/29868176
http://dx.doi.org/10.1136/lupus-2017-000254

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