Gemcabene downregulates inflammatory, lipid-altering and cell-signaling genes in the STAM™ model of NASH

BACKGROUND AND AIMS: Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) can advance, if untreated, to liver fibrosis, cirrhosis, hepatocellular carcinoma, liver failure and liver-related death. In the United States, NASH affects approximately 2–5% of the population an...

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Detalles Bibliográficos
Autores principales: Oniciu, Daniela Carmen, Hashiguchi, Taishi, Shibazaki, Yuichiro, Bisgaier, Charles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976190/
https://www.ncbi.nlm.nih.gov/pubmed/29847555
http://dx.doi.org/10.1371/journal.pone.0194568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976190/
https://www.ncbi.nlm.nih.gov/pubmed/29847555
http://dx.doi.org/10.1371/journal.pone.0194568

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