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Gemcabene downregulates inflammatory, lipid-altering and cell-signaling genes in the STAM™ model of NASH
BACKGROUND AND AIMS: Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) can advance, if untreated, to liver fibrosis, cirrhosis, hepatocellular carcinoma, liver failure and liver-related death. In the United States, NASH affects approximately 2–5% of the population an...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976190/ https://www.ncbi.nlm.nih.gov/pubmed/29847555 http://dx.doi.org/10.1371/journal.pone.0194568 |