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Design of a glutamine substrate tag enabling protein labelling mediated by Bacillus subtilis transglutaminase

Transglutaminases (TGases) are enzymes that catalyse protein cross-linking through a transamidation reaction between the side chain of a glutamine residue on one protein and the side chain of a lysine residue on another. Generally, TGases show low substrate specificity with respect to their amine su...

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Detalles Bibliográficos
Autores principales: Oteng-Pabi, Samuel K., Clouthier, Christopher M., Keillor, Jeffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976192/
https://www.ncbi.nlm.nih.gov/pubmed/29847605
http://dx.doi.org/10.1371/journal.pone.0197956