Kinetic and structural comparison of a protein’s cotranslational folding and refolding pathways

Precise protein folding is essential for the survival of all cells, and protein misfolding causes a number of diseases that lack effective therapies, yet the general principles governing protein folding in the cell remain poorly understood. In vivo, folding can begin cotranslationally and protein qu...

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Detalles Bibliográficos
Autores principales: Samelson, Avi J., Bolin, Eric, Costello, Shawn M., Sharma, Ajeet K., O’Brien, Edward P., Marqusee, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976279/
https://www.ncbi.nlm.nih.gov/pubmed/29854950
http://dx.doi.org/10.1126/sciadv.aas9098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976279/
https://www.ncbi.nlm.nih.gov/pubmed/29854950
http://dx.doi.org/10.1126/sciadv.aas9098

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