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Co-translational protein targeting facilitates centrosomal recruitment of PCNT during centrosome maturation in vertebrates

As microtubule-organizing centers of animal cells, centrosomes guide the formation of the bipolar spindle that segregates chromosomes during mitosis. At mitosis onset, centrosomes maximize microtubule-organizing activity by rapidly expanding the pericentriolar material (PCM). This process is in part...

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Detalles Bibliográficos
Autores principales: Sepulveda, Guadalupe, Antkowiak, Mark, Brust-Mascher, Ingrid, Mahe, Karan, Ou, Tingyoung, Castro, Noemi M, Christensen, Lana N, Cheung, Lee, Jiang, Xueer, Yoon, Daniel, Huang, Bo, Jao, Li-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976437/
https://www.ncbi.nlm.nih.gov/pubmed/29708497
http://dx.doi.org/10.7554/eLife.34959