mTORC1 and mTORC2 differentially promote natural killer cell development

Natural killer (NK) cells are innate lymphoid cells that are essential for innate and adaptive immunity. Mechanistic target of rapamycin (mTOR) is critical for NK cell development; however, the independent roles of mTORC1 or mTORC2 in regulating this process remain unknown. Ncr1(iCre)-mediated delet...

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Detalles Bibliográficos
Autores principales: Yang, Chao, Tsaih, Shirng-Wern, Lemke, Angela, Flister, Michael J, Thakar, Monica S, Malarkannan, Subramaniam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976438/
https://www.ncbi.nlm.nih.gov/pubmed/29809146
http://dx.doi.org/10.7554/eLife.35619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976438/
https://www.ncbi.nlm.nih.gov/pubmed/29809146
http://dx.doi.org/10.7554/eLife.35619

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