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Immunohistochemically detectable metallothionein expression in malignant pleural mesotheliomas is strongly associated with early failure to platin-based chemotherapy

BACKGROUND: Malignant pleural mesothelioma (MPM) is a biologically highly aggressive tumor arising from the pleura with a dismal prognosis. Cisplatin is the drug of choice for the treatment of MPM, and carboplatin seems to have comparable efficacy. Nevertheless, cisplatin treatment results in a resp...

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Detalles Bibliográficos
Autores principales: Mairinger, Fabian D., Schmeller, Jan, Borchert, Sabrina, Wessolly, Michael, Mairinger, Elena, Kollmeier, Jens, Hager, Thomas, Mairinger, Thomas, Christoph, Daniel C., Walter, Robert F.H., Eberhardt, Wilfried E.E., Plönes, Till, Wohlschlaeger, Jeremias, Jasani, Bharat, Schmid, Kurt Werner, Bankfalvi, Agnes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976462/
https://www.ncbi.nlm.nih.gov/pubmed/29854276
http://dx.doi.org/10.18632/oncotarget.24962