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LSCC SNP variant regulates SOX2 modulation of VDAC3

Lung squamous cell carcinoma (LSCC) is a genomically complex malignancy with no effective treatments. Recent studies have found a large number of DNA alterations such as SOX2 amplification in LSCC patients. As a stem cell transcription factor, SOX2 is important for the maintenance of pluripotent cel...

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Detalles Bibliográficos
Autores principales: Chyr, Jacqueline, Guo, Dongmin, Zhou, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976468/
https://www.ncbi.nlm.nih.gov/pubmed/29854282
http://dx.doi.org/10.18632/oncotarget.24918