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Atomistic molecular dynamics simulations of bioactive engrailed 1 interference peptides (EN1-iPeps)
The neural-specific transcription factor Engrailed 1 - is overexpressed in basal-like breast tumours. Synthetic interference peptides - comprising a cell-penetrating peptide/nuclear localisation sequence and the Engrailed 1-specific sequence from the N-terminus have been engineered to produce a stro...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976472/ https://www.ncbi.nlm.nih.gov/pubmed/29854286 http://dx.doi.org/10.18632/oncotarget.25025 |