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Atomistic molecular dynamics simulations of bioactive engrailed 1 interference peptides (EN1-iPeps)

The neural-specific transcription factor Engrailed 1 - is overexpressed in basal-like breast tumours. Synthetic interference peptides - comprising a cell-penetrating peptide/nuclear localisation sequence and the Engrailed 1-specific sequence from the N-terminus have been engineered to produce a stro...

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Detalles Bibliográficos
Autores principales: Gandhi, Neha S., Blancafort, Pilar, Mancera, Ricardo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976472/
https://www.ncbi.nlm.nih.gov/pubmed/29854286
http://dx.doi.org/10.18632/oncotarget.25025