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Improved sensitivity for detection of breast cancer by combination of miR-34a and tumor markers CA 15-3 or CEA

BACKGROUND: MicroRNAs biomarkers have shown value for diagnosis and prognosis of various cancers. Combination with established tumor markers has rarely been done. RESULTS: Breast cancer patients had significantly higher serum RNA loads (AUC 0.665), lower miR-34a (AUC 0.772), higher CEA and CA 15-3 l...

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Detalles Bibliográficos
Autores principales: Zaleski, Martin, Kobilay, Makbule, Schroeder, Lars, Debald, Manuel, Semaan, Alexander, Hettwer, Karina, Uhlig, Steffen, Kuhn, Walther, Hartmann, Gunther, Holdenrieder, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976482/
https://www.ncbi.nlm.nih.gov/pubmed/29854296
http://dx.doi.org/10.18632/oncotarget.25077