Macrophages regulate lung ILC2 activation via Pla2g5-dependent mechanisms

Group V phospholipase A(2) (Pla2g5) is a lipid-generating enzyme necessary for macrophage effector functions in pulmonary inflammation. However, the lipid mediators involved and their cellular targets have not been identified. Mice lacking Pla2g5 showed markedly reduced lung ILC2 activation and eosi...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Munehiro, Samuchiwal, Sachin K., Quehenberger, Oswald, Boyce, Joshua A., Balestrieri, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976507/
https://www.ncbi.nlm.nih.gov/pubmed/29346348
http://dx.doi.org/10.1038/mi.2017.99

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976507/
https://www.ncbi.nlm.nih.gov/pubmed/29346348
http://dx.doi.org/10.1038/mi.2017.99

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