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Macrophages regulate lung ILC2 activation via Pla2g5-dependent mechanisms
Group V phospholipase A(2) (Pla2g5) is a lipid-generating enzyme necessary for macrophage effector functions in pulmonary inflammation. However, the lipid mediators involved and their cellular targets have not been identified. Mice lacking Pla2g5 showed markedly reduced lung ILC2 activation and eosi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976507/ https://www.ncbi.nlm.nih.gov/pubmed/29346348 http://dx.doi.org/10.1038/mi.2017.99 |