Endothelial Smoothened-dependent Hedgehog Signaling is Not Required for Sonic Hedgehog Induced Angiogenesis or Ischemic Tissue Repair

Sonic Hedgehog (Shh) signaling induces neovascularization and angiogenesis. It is not known whether hedgehog signaling pathway in endothelial cells is essential to angiogenesis. Smoothened (Smo) transduces hedgehog signaling across the cell membrane. This study assessed whether endothelial Smoothene...

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Detalles Bibliográficos
Autores principales: Gupta, Rajesh, Mackie, Alexander R., Misener, Sol, Liu, Lijun, Losordo, Douglas W., Kishore, Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976512/
https://www.ncbi.nlm.nih.gov/pubmed/29453401
http://dx.doi.org/10.1038/s41374-018-0028-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976512/
https://www.ncbi.nlm.nih.gov/pubmed/29453401
http://dx.doi.org/10.1038/s41374-018-0028-5

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