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The C/EBPβ LIP isoform rescues loss of C/EBPβ function in the mouse

The transcription factor C/EBPβ regulates hematopoiesis, bone, liver, fat, and skin homeostasis, and female reproduction. C/EBPβ protein expression from its single transcript occurs by alternative in-frame translation initiation at consecutive start sites to generate three isoforms, two long (LAP*,...

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Detalles Bibliográficos
Autores principales: Bégay, Valérie, Baumeier, Christian, Zimmermann, Karin, Heuser, Arnd, Leutz, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976626/
https://www.ncbi.nlm.nih.gov/pubmed/29849099
http://dx.doi.org/10.1038/s41598-018-26579-y