Klotho is upregulated in human cardiomyopathy independently of circulating Klotho levels

Klotho is an antiaging protein which exerts known cardioprotection. In kidney, trans-membrane Klotho acts as essential co-receptor of fibroblast growth factor 23 (FGF23). In the heart, soluble Klotho (sKlotho) protects from systolic dysfunction independently of FGF23. Here, we analyzed the associati...

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Detalles Bibliográficos
Autores principales: Poelzl, G., Ghadge, S. K., Messner, M., Haubner, B., Wuertinger, Ph., Griesmacher, A., Doerler, J., Ensinger, C., Ulmer, H., Zaruba, M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976633/
https://www.ncbi.nlm.nih.gov/pubmed/29849175
http://dx.doi.org/10.1038/s41598-018-26539-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976633/
https://www.ncbi.nlm.nih.gov/pubmed/29849175
http://dx.doi.org/10.1038/s41598-018-26539-6

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