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Environmental responsiveness of tubulin glutamylation in sensory cilia is regulated by the p38 MAPK pathway

Glutamylation is a post-translational modification found on tubulin that can alter the interaction between microtubules (MTs) and associated proteins. The molecular mechanisms regulating tubulin glutamylation in response to the environment are not well understood. Here, we show that in the sensory c...

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Detalles Bibliográficos
Autores principales: Kimura, Yoshishige, Tsutsumi, Koji, Konno, Alu, Ikegami, Koji, Hameed, Saira, Kaneko, Tomomi, Kaplan, Oktay Ismail, Teramoto, Takayuki, Fujiwara, Manabi, Ishihara, Takeshi, Blacque, Oliver E., Setou, Mitsutoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976657/
https://www.ncbi.nlm.nih.gov/pubmed/29849065
http://dx.doi.org/10.1038/s41598-018-26694-w