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Mapping of Adenovirus of serotype 3 fibre interaction to desmoglein 2 revealed a novel ‘non-classical’ mechanism of viral receptor engagement

High-affinity binding of the trimeric fibre protein to a cell surface primary receptor is a common feature shared by all adenovirus serotypes. Recently, a long elusive species B adenovirus receptor has been identified. Desmoglein 2 (DSG2) a component of desmosomal junction, has been reported to inte...

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Detalles Bibliográficos
Autores principales: Vassal-Stermann, Emilie, Mottet, Manon, Ducournau, Corinne, Iseni, Frédéric, Vragniau, Charles, Wang, Hongjie, Zubieta, Chloe, Lieber, André, Fender, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976663/
https://www.ncbi.nlm.nih.gov/pubmed/29849084
http://dx.doi.org/10.1038/s41598-018-26871-x