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Identification of a peptide for folate receptor alpha by phage display and its tumor targeting activity in ovary cancer xenograft

The expression level of folate receptor alpha (FRα) is located highly rate in ovarian cancer though it is remained absent in normal tissues. This highly tumor restricted expression profile makes FRα a promising target for tumor therapy and diagnosis. In this research we report a FRα binding peptide...

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Detalles Bibliográficos
Autores principales: Xing, Lijun, Xu, Yifeng, Sun, Keyong, Wang, Hong, Zhang, Fengguo, Zhou, Zhengpin, Zhang, Juan, Zhang, Fang, Caliskan, Bilgen, Qiu, Zheng, Wang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976665/
https://www.ncbi.nlm.nih.gov/pubmed/29849110
http://dx.doi.org/10.1038/s41598-018-26683-z