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Identification of a peptide for folate receptor alpha by phage display and its tumor targeting activity in ovary cancer xenograft
The expression level of folate receptor alpha (FRα) is located highly rate in ovarian cancer though it is remained absent in normal tissues. This highly tumor restricted expression profile makes FRα a promising target for tumor therapy and diagnosis. In this research we report a FRα binding peptide...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976665/ https://www.ncbi.nlm.nih.gov/pubmed/29849110 http://dx.doi.org/10.1038/s41598-018-26683-z |