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Recovering Actives in Multi-Antitarget and Target Design of Analogs of the Myosin II Inhibitor Blebbistatin

In multitarget drug design, it is critical to identify active and inactive compounds against a variety of targets and antitargets. Multitarget strategies thus test the limits of available technology, be that in screening large databases of compounds vs. a large number of targets, or in using in sili...

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Detalles Bibliográficos
Autores principales: Roman, Bart I., Guedes, Rita C., Stevens, Christian V., García-Sosa, Alfonso T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976736/
https://www.ncbi.nlm.nih.gov/pubmed/29881723
http://dx.doi.org/10.3389/fchem.2018.00179